| Hardcopy Reference: |
HH-11-07-240 |
| Title: |
A Comparative Study of the Preventive Use of Tilmicosin Phosphate (Pulmotil premix) and Mycoplasma hyopneumoniae Vaccination in a Pig Herd with Chronic Respiratory Disease |
| Author(s): |
B. MATEUSEN, D. MAES, G. HOFLACK, M. VERDONCK and A. DE KRUIF |
| Publication Year: |
2001 |
| Reference: |
J. Vet. Med. B 48, 733-741 (2001) |
| Country: |
Belgium |
| Summary: |
|
| Abstract: |
This study was conducted to compare the effects of a preventive in-feed medication
programme using tilmicosin (Pulmotil)200 premix, Elanco Animal Health) at 200 p.p.m. with
those of a Mycoplasma hyopneumoniae (Mh) vaccination programme (StellamuneTM Mycoplasma, P®zer
Animal Health). A pig herd with chronic respiratory disease in which infection with Mh played an
important role was selected, and a total of 204 piglets were randomly allocated to either the
medication (P) or the vaccination (V) group. Pigs in the P group received medicated feed for
3 weeks after weaning (days 34±55), and for 2 weeks late in the nursery period (days 77±98). The
piglets in the V group were vaccinated twice intramuscularly, at 4 and 22 days of age. The two
groups were compared on the basis of average daily gain (ADG), feed conversion rate (FCR),
additional curative medication days (CMD), overall mortality (major variables), a coughing index,
pneumonia lesions, and serology against Mh, in¯uenza H1N1 and in¯uenza H3N2 viruses,
Actinobacillus pleuropneumoniae (App) and porcine reproductive and respiratory syndrome virus
(PRRSV) (minor variables). No signi®cant differences (P > 0.05) were observed for ADG (555 g/
day in P group; 567 g/day in V group), FCR (2.64 in P group; 2.41 in V group) and mortality rate
(11% in P group; 7% in V group). The average number of additional curative medication days
(CMD) per pig was signi®cantly higher (P < 0.01) in the P group (1.5) than in the V group (0.58). At
slaughter age, the serological results and the prevalence of macroscopic lung lesions were
comparable in the two groups (P > 0.05). With the exception of CMD, the preventive use of
tilmicosin at this swine farm was found to confer similar bene®cial effects to Mh vaccination. |
| Database: |
Welfare |
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